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Osler-Weber-Rendu syndrome is a disorder where excessive bleeding can occur due to abnormal blood vessels. Associated bleeding may occur through the skin or internally. Primarily, treatment at the Vascular Birthmark Center should revolve around addressing the abnormal blood vessels. However, in severe cases, patients often require a blood transfusion. Complications from Osler-Weber-Rendu syndrome may include cirrhosis of the liver or sudden heart failure, although these cases are not typical of the disorder.

The disorder results in a type of arteriovenous malformation, which can affect the skin, along with the connections between arteries and capillaries in the brain, lungs or liver. Four specific genes have been identified as contributing to Osler-Weber-Rendu syndrome, and the disorder has been confirmed as hereditary.

Common Symptoms

Symptoms vary in Osler-Weber-Rendu syndrome, depending on where the abnormal blood vessels are located in the body. One of the most common symptoms, usually first to appear, is nosebleeds that begin in the teenage years. Visible signs, such as telangiectasias blood vessels in the skin, normally do not present until the sufferer reaches his or her twenties or thirties.

Other symptoms may include abnormal blood vessels that develop on the lips and even the whites of the eyes, vomiting blood, passing dark or bloody stools and sudden onset of fatigue, often accompanied by feeling weak and faint.

Osler-Weber-Rendu Syndrome Treatment

If significantly severe bleeding occurs, the patient will in all likelihood need a blood transfusion. Such cases will require specialist intervention, as there is a higher risk of complications arising from your Osler-Weber-Rendu syndrome. When bleeding is mainly occurring in the skin, laser therapy can be used to treat the affected areas as part of managing the condition.

It is also important to address arteriovenous malformations (AVMs) as unregulated blood flow can put added pressure on the heart and lead to sudden heart failure. An embolization is recommended to block any abnormal blood vessels and significantly reduce associated risks. Women suffering from Osler-Weber-Rendu syndrome are often encouraged to take the combined oral contraceptive pill, as female hormones have shown positive results in managing Osler-Weber-Rendu syndrome symptoms.

Before pursuing any treatment, it is important to receive an accurate diagnosis from a physician who is qualified to recognize Osler-Weber-Rendu syndrome. The Vascular Birthmark Center is equipped to assess patients of all ages wishing to pursue a diagnosis of and treatment for vascular malformations. Getting the diagnosis right is crucial, as the wrong treatment can have an opposite effect than that which was intended.

Reach out Today

You can reach out to the Vascular Birthmark Center today if you have any further questions or have developed symptoms which you suspect may be linked to Osler-Weber-Rendu syndrome. We will take a list of your symptoms, a detailed medical and family history and advise you right away if we feel you should attend our offices for a full evaluation.

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Abril M.

Dr. Levitin is very knowledgeable, compassionate and professional. Five years ago, I needed to find information about a birth mark that my newborn daughter started to grow a couple days after birth. I was afraid, I did not feel like I got any clear information about it through my insurance; also, they did not offer any course of treatment for it. I started to look for information, the birthmark was growing each day, information was scarce and I just got more scared. Finally, I found a video in Youtube from a grandmother who was very grateful after finding treatment for her grand daughter through The Birthmark Foundation. It was a huge blessing to me and my family. I found Dr. Levitin, I contacted him thinking he probably would not even answer. I was wrong, he kindly answered promptly, got in touch with me and soon he had a plan : ) I went to see him at the Birthmark Center in Los Angeles. He explained everything in a way that it was so clear to understand, no question I made was insignificant and his answers were each very informative. I really never have had an experience with a doctor who explains and speaks in such a way. I left his office knowing that my daughter was in the best hands and the best care. I first thank God for the Birthmark Foundation, a great organization with the highest quality of doctors. Also, a very special thanks to Dr. Levitin for all his help and kindness, for listening to my concerns and answering each and every question. And last, but no least, to the Birthmark Foundation Center in Los Angeles : ) I hope many children can find help/care in this place as I found it for my daughter. Thank you forever.

Ryan E.

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Danielle L.

we are forever grateful for Dr. Levitin. My daughter Lena had surgery to remove her hemangioma that was located on her forehead at just 6 month old. she healed beautifully and we couldn't be happier with how minimal her scar is, even almost 4.5 years later. Dr. Levitin is caring, compassionate, and such a great doctor/surgeon overall. He had our daughter's best interest and I knew she was in good hands. I highly recommend him any chance I get!

Chris

My name is Chris and I was recently treated for an AVM on my forehead by Dr. Gregory Levitin of New York (New York Eye and Ear Infirmary). Thankfully, I live within a few hours of NYC. In brief, I would like to say that Dr. Levitin is very capable doctor with a lot of experience with AVMs. He responds quickly to e-mail, texts, and phone calls. He accepts insurance. He takes a "team approach" and will be your "QB" and involve other specialists as necessary. In my particular case they were Dr. Raj Shrivastava (Mt Sinai) and Dr. Raphael A. Ortiz (Lenox Hill) in NY. I recommend contacting Dr Levitin for a consultation if you suspect you have an AVM. All 3 Drs are just good people. When I spoke to them, they treated me like like an equal. I felt like they were advising me as a close friend or family member. Like many that suffer with AVMs I was at first mis-diagnosed. What was thought to be a just a simple cyst turned out to be an AVM. Surgery to remove the cyst made the AVM about 5x bigger. My treatment entailed a few MRIs and CAT scans to determine what was going on and the treatment plan. This was followed by consultation with the 3 Drs mentioned above and finally a 2-day procedure. On day 1 Dr Ortiz embolized the AVM. On day 2 Dr Levitin and Dr Shrivastava removed the AVM from my skull and put some metal mesh there to fill the "hole". It has been 6-months since the surgery and so far I have not had any recurrence. In honor of Vascular Birthmark Awareness Day and to thank these Drs for all they have done for me, I just want to give everyone a solid reference. Finding the right doctor for this type of stuff makes all the difference.

Valle S.

I just discovered this page i have also a birthmark I always experiences bully because of this. I don't know what kind of birthmark is this if it is harmful ? I hope Dr. Levitin notice this message in this way I think he can help me :) :) #DrLevitin

Alicia M.

This year marks the 10th that I contacted VBF for help. Since then I have been under the care of Dr. G Levitin and Dr. R. Ortiz, they are my guardian healing angels! Thanks VBF for not only helping me but also for letting me be a volunteer in the foundation whenever I am needed. A Big Hug to all from MIAMI... Alicia

Alexander G.

Totally positive experience. Dr. Levitin is a great professional. He has diagnosed and treated my nose breathing problem, significantly improving my quality of life. Office staff is very professional. Appointments always kept on time. Strongly recommend.